Pathogenic bacterium susceptible to Abp118 bacteriocin

Pathogenic bacteria susceptible to Abp118 bacteriocin" refers collectively to bacterial species that are inhibited or killed by the action of the antimicrobial peptide known as **Abp118**, which is produced by certain strains of Lactobacillus salivarius. These include notable pathogens such as *Listeria monocytogenes* and some strains of *Escherichia coli*, among others. The mechanism involves direct interaction with the bacterial cell membrane, leading to pore formation, membrane disruption, and ultimately cell death[2][4]. This group is not a single molecular entity but rather encompasses various pathogenic bacteria sharing susceptibility due to their membrane composition or presence/absence of specific receptors for this class IIb two-peptide bacteriocin. While these bacteria are important in disease contexts—especially foodborne illness—they do not represent a canonical drug target like an enzyme or receptor; instead, they are defined operationally based on their sensitivity profile. Therefore, this entry does not correspond precisely with standard therapeutic targets but is used functionally in research on novel antimicrobials such as probiotics producing specific bacteriocins[1][2][3]. **Note:** This entry describes a heterogeneous group rather than an individual molecule/receptor; it should be flagged as "is_incorrect: true" for structured databases seeking discrete molecular targets.

Other names

Pathogenic bacteria targeted by Abp118Bacteria sensitive to Abp118Abp118-susceptible pathogens

Pore formation and membrane disruption by the bacteriocin[2][4]