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Target intelligence / Profile preview
Pathogenic Intestinal Bacteria
- Molecular classification
- Bacteria, Microorganism
01
Overview
Pathogenic intestinal bacteria are bacterial species that colonize the gastrointestinal tract and possess the capacity to cause disease in humans. They utilize various virulence factors to adhere to and invade epithelial cells, evade immune responses, and produce toxins. Infection with these pathogens can result in acute gastroenteritis, chronic inflammatory conditions, or systemic illness. Their interaction with the host microbiome is complex, with pathogens often inducing inflammation that disrupts commensal populations.
- Other names
- Enteric PathogensPathogenic Gut BacteriaIntestinal Pathogens
02
Mechanism of action
Antibiotic therapy targets bacterial viability and replication.
03
Biological functions
Colonization of the gastrointestinal tractInvasion of host tissuesToxin productionImmune evasionDisruption of gut function
04
Disease associations
GastroenteritisColitisSystemic InfectionsCrohn's Disease (implicated)
05
Safety considerations
Antibiotic resistanceDisruption of the gut microbiomeOvergrowth of opportunistic pathogens (e.g., Clostridioides difficile)
06
Interacting drugs
Antibiotics
07
Biomarkers
Presence of specific bacterial species in stool samplesInflammatory markers (e.g., fecal calprotectin)
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