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Target intelligence / Profile preview
Pathogenic Microorganisms (Gardnerella vaginalis, Prevotella bivia, Candida albicans)
- Molecular classification
- Bacterium, Fungus
01
Overview
This target refers to a group of pathogenic microorganisms, including Gardnerella vaginalis, Prevotella bivia, and Candida albicans, commonly associated with infections in the female genital tract. Each organism has unique biological characteristics and clinical significance, contributing to conditions like bacterial vaginosis and vulvovaginal candidiasis. Effective treatment strategies need to consider the polymicrobial nature of these infections and the potential for antibiotic resistance.
- Other names
- Bacterial vaginosis pathogensVulvovaginal candidiasis pathogensVaginal flora pathogens
02
Mechanism of action
Antibacterial; Antifungal
03
Biological functions
ColonizationInfectionBiofilm formationTissue degradation
04
Disease associations
Bacterial vaginosisVulvovaginal candidiasisPelvic inflammatory diseasePreterm birthHIV transmission/acquisitionAbscessesOsteomyelitisNecrotizing fasciitis
05
Safety considerations
Antibiotic resistanceRecurrent infectionsAdverse drug reactions
06
Interacting drugs
Metronidazole
4 more in the full profile.
07
Biomarkers
Vaginal pHNugent scoreAmsel's criteria
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