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PCDH9 antisense RNA 2 (non-protein coding) (PCDH9-AS2)
- Target
- PCDH9-AS2
- Molecular classification
- Long non-coding RNA (lncRNA), Non-protein coding RNA, Antisense RNA, Other
01
Overview
PCDH9 antisense RNA 2 (PCDH9-AS2) is a long non-coding antisense RNA gene located on chromosome 13, transcribed in the opposite direction to the protein-coding PCDH9 gene[2][4][6][7]. It does not encode a protein. Instead, it is predicted to regulate PCDH9 expression through cis-regulatory mechanisms, which may in turn influence the biological functions of the PCDH9 protein in cell-cell adhesion, formation of cell junctions, and neuronal connectivity[2]. Despite these predicted roles, the exact biological functions of PCDH9-AS2, and any direct involvement in disease, remain to be fully elucidated[2]. There are currently no reported drugs that target PCDH9-AS2, and it is not considered a canonical therapeutic target (such as a receptor, enzyme, or transporter)[2][6][7].
- Other names
- PCDH9-AS2PCDH9 antisense RNA 2PCDH9 antisense RNA 2 (non-protein coding)
02
Biological functions
Cis-regulation of PCDH9 gene expressionRegulation of cell junction formation (predicted)Possible role in neuronal connectivity (predicted)
03
Disease associations
Other (Potential involvement in neurological development or disease, but unproven)
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