PDCD10 and GCKIII kinases-associated protein 1 (PGCKA1)

PDCD10 and GCKIII kinases-associated protein 1 (PGCKA1) is a protein-coding gene associated with tumor suppressor activity, particularly in colorectal cancer, by targeting the KEAP1/USP17/ELK1/CDK6 signaling axis[3][5][9]. It is also linked to regulation of the cell cycle and is implicated in cranioectodermal dysplasia 1[3][4]. The gene is also referenced under alternative names such as C4orf19 and FLJ11017[2][3]. However, there is limited information on whether it is an established therapeutic target or directly targeted by any drugs. Based on available sources, PGCKA1 does not currently qualify as a widely recognized drug target, is sometimes described as an "uncharacterized protein," and may be confused due to synonym redundancy or insufficient characterization[2][3].

Other names

C4orf19FLJ110170610040J01Rikuncharacterized protein C4orf19