PDGFA divergent transcript (PDGFA-DT)

PDGFA divergent transcript (PDGFA-DT), also known as HRAT92 or heart tissue-associated transcript 92, is a long non-coding RNA gene located on chromosome 7 in humans. It is named for its genomic proximity and divergent orientation relative to the PDGFA gene (platelet-derived growth factor subunit A), but it is not a protein-coding gene, nor is it a receptor, enzyme, transporter, or other classical drug target. There is insufficient functional data and no established biological or disease roles in major databases as of the current knowledge. Based on available resources, it does not have recognized interacting drugs, biomarker status, or direct therapeutic relevance. The abbreviation PDGFA-DT may be confused with the platelet-derived growth factor A protein or its receptor genes (PDGFA, PDGFRA), which have well-characterized roles in cell signaling and cardiovascular biology. However, this particular entry refers to a distinct lncRNA (non-protein-coding) that is different from those established targets. Therefore, it is important not to conflate PDGFA-DT (PDGFA divergent transcript) with the PDGF family of proteins or receptors. In summary, the PDGFA divergent transcript is not a standard therapeutic target, but rather, it's an under-characterized noncoding RNA for which insufficient molecular or clinical detail is currently available to populate standard target fields.

Other names

HRAT92heart tissue-associated transcript 92