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PDZ and LIM domain 7 pseudogene
- Molecular classification
- Other (pseudogene; not protein-coding)
01
Overview
PDZ and LIM domain 7 pseudogene (ENSG00000253907) is a non-protein-coding sequence highly similar to the PDZ and LIM domain 7 gene (PDLIM7). Pseudogenes may arise through duplication or retrotransposition and are generally considered non-functional relics, though some have identified roles as RNA-based regulators in human disease (e.g., as competitive endogenous RNAs that interfere with microRNA regulation of their protein-coding counterpart)[5]. There is no clear evidence that this pseudogene, specifically, has established functional roles, therapeutic importance, or is used as a target in drug development. The canonical PDLIM7 gene encodes for an adapter/scaffolding protein involved in actin filament organization and cellular signaling, but its pseudogene version in question does not encode a functional protein, and its biological relevance is currently unclear[1][3][4][5].
- Other names
- PDZ and LIM domain protein 7 pseudogene
02
Biological functions
Pseudogenes generally lack direct protein functionNo clear functional role as regulatory noncoding RNA reported for this specific pseudogene
03
Disease associations
None specifically reported for this pseudogenePseudogenes in general may influence diseases as competitive endogenous RNAs (not confirmed for this specific entry)
04
Biomarkers
None specificNo documented use as a biomarker
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