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PELO antisense RNA 1 (PELO-AS1)

Target: PELO-AS1
Molecular classification: Long noncoding RNA (lncRNA), Non-coding RNA

Overview

PELO antisense RNA 1 (PELO-AS1) is a human long noncoding RNA, meaning it is a functional RNA molecule transcribed from DNA but not translated into protein[3][7]. It is affiliated with the class of lncRNAs (long noncoding RNAs), and its locus is listed under several external databases (HGNC: 56263, NCBI Gene: 125775243, Ensembl: ENSG00000248898)[3]. LncRNAs, including antisense RNAs like PELO-AS1, typically modulate gene expression by interacting with regulatory elements, chromatin, and sometimes mRNA itself, impacting transcription, translation, and epigenetic marks[4]. No current evidence supports PELO-AS1 as a therapeutic target, disease-associated RNA, or biomarker, and there are no known drugs that directly interact with or target PELO-AS1.

Other names: CTD-2288O8.1PELO-AS1

Biological functions

Regulation of gene expression (by antisense RNA mechanisms)chromatin modification (general for antisense RNAs)

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