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PELP1 divergent transcript (PELP1-DT)

Target
PELP1-DT
Molecular classification
Long non-coding RNA (lncRNA)
01

Overview

PELP1 divergent transcript (PELP1-DT, also known as lnc-EST885) is a long non-coding RNA located at chromosome 17:4704095-4705770 (hg38) near the PELP1 gene[5]. It is catalogued in major gene annotation resources but currently has no well-documented biological function or disease association. As a lncRNA, its potential functions could include regulation of neighboring gene expression or broader chromatin-associated activities[4][6], but no experimental data exist in the scientific literature to confirm such functions for PELP1-DT specifically. There are no known drug interactions, disease associations, or biomarker usage reported for this transcript. PELP1-DT should not be confused with PELP1 (Proline, glutamate and leucine rich protein 1), which is a protein-coding gene serving as a coregulator of nuclear receptors and having important roles in cancer and other biological pathways[1][3][7]. The current lack of biological or clinical information for PELP1-DT means it cannot be considered a therapeutic target at this time. Aliases such as lnc-EST885 all refer to the same lncRNA entry[5].

Other names
lnc-EST885PELP1-DT[5]
02

Mechanism of action

None known.

03

Biological functions

Currently unclear; as a lncRNA, potential roles could include regulation of gene expression, chromatin organization, or other RNA-mediated mechanisms, but specific functions for PELP1-DT are not established[4][6]
04

Disease associations

Not established for this transcript; no direct evidence links PELP1-DT to disease.

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