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Antibiotics targeting bacterial cell wall synthesis primarily inhibit penicillin-binding proteins (PBPs) or peptidoglycan precursor formation. Those targeting protein synthesis act on bacterial ribosomes. Both exploit prokaryotic-eukaryotic differences for selective antibacterial action. Resistance mechanisms include beta-lactamases, target modification, and altered drug entry/efflux.
Inhibition of bacterial cell wall synthesis or protein synthesis.
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