Drug pipeline
Full profile accessExplore the programs pursuing this target and their development progress.
- Drug candidates
- Developers
- Development stage
Target intelligence / Profile preview
Peptidyl Transferase (Large Ribosomal Subunit) (PTC)
- Target
- PTC
- Molecular classification
- Ribozyme, RNA enzyme
01
Overview
Peptidyl transferase is a ribozyme located in the large subunit of the ribosome. It catalyzes two essential reactions during protein synthesis: formation of peptide bonds between adjacent amino acids and hydrolysis of peptidyl-tRNA, releasing the completed polypeptide chain at translation termination. The catalytic center (PTC) is composed entirely of rRNA. Many antibiotics target this center to inhibit bacterial protein synthesis.
02
Mechanism of action
Inhibition of bacterial protein synthesis by binding to the peptidyl transferase center.
03
Biological functions
Peptide bond formationHydrolysis of peptidyl-tRNAProtein synthesis
04
Disease associations
Infection
05
Safety considerations
Antibiotic resistance
06
Interacting drugs
Antibiotics (various)
Beyond the preview
Go deeper on Peptidyl Transferase (Large Ribosomal Subunit) (PTC).
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Clinical trials
Full profile accessFollow the clinical studies evaluating therapies directed at this target.
- Trial design
- Status
- Readouts
Competitive landscape
Full profile accessCompare approaches across drug candidates, modalities, and indications.
- Programs
- Modalities
- Indications
Literature & evidence
Full profile accessInvestigate the research and source evidence behind target biology and development.
- Publications
- Sources
- Analysis
Patents
Full profile accessExplore patent activity around therapies and technologies addressing this target.
- Patents
- Assignees
- Technologies
Research & analysis
Full profile accessConnect target biology, drug development, and emerging evidence in your research.
- Biology
- Development news
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on Peptidyl Transferase (Large Ribosomal Subunit) (PTC).