Peptidylprolyl isomerase A pseudogene 1 (PPIAP1)

Peptidylprolyl isomerase A pseudogene 1 is a human genetic locus classified as a pseudogene, meaning it is a non-functional genomic sequence similar to a protein-coding gene but typically lacking the ability to code for a functional protein[2]. It is related to the parental gene PPIA, which encodes cyclophilin A, a peptidyl-prolyl cis-trans isomerase involved in protein folding, immune response, and other cellular processes[1][4]. Pseudogenes such as PPIAP1 may have regulatory functions at the RNA level, for example, acting as decoys for microRNAs or influencing the expression of their parental or other genes, but they are not considered therapeutic targets or druggable entities themselves[10]. Based on available evidence, PPIAP1 should not be considered a molecular target for drug development or biological research in the same manner as functional enzymes, receptors, or transporters. Its main biological relevance would likely be as a possible regulator at the RNA level, but this remains an area of basic research and not established clinical or translational medicine.

Other names

peptidylprolyl isomerase A (cyclophilin A), pseudogene 1cyclophilin A pseudogene 1