Target intelligence / Profile preview

Peptidylprolyl isomerase A pseudogene 10 (PPIAP10)

Target
PPIAP10
Molecular classification
Other (Pseudogene, long non-coding RNA)
01

Overview

Peptidylprolyl isomerase A pseudogene 10 (PPIAP10) is a human pseudogene located on chromosome 1 that is related to the protein-coding Peptidylprolyl isomerase A (PPIA) gene[3]. As a pseudogene, it does not encode an active protein but may represent a nonfunctional copy or a member of the long non-coding RNA family. While some pseudogenes have been shown to act as competitive endogenous RNAs (ceRNAs) or participate in regulatory networks (e.g., PPIAP22 affects PPIA expression in cancer), there is currently no reported biological function, disease association, drug interaction, or biomarker utility for PPIAP10 in the literature[3][4]. Its aliases reflect sequence and functional similarity to both PPIA and other cyclophilin pseudogenes. The canonical abbreviation is PPIAP10.\n\nNote: The main scientific literature and databases do not describe PPIAP10 as a therapeutic target, nor is there evidence it is misspelled or incorrect based on current gene nomenclature. It remains classified as a pseudogene; any biological activity that influences disease or drug response has only been attributed to related pseudogenes (e.g., PPIAP22) and its parental gene PPIA, not PPIAP10 itself[3][4].

Other names
CRPCyclophilin related pseudogenePPIAL2PPIP10dJ823G15.1Peptidylprolyl isomerase (cyclophilin) pseudogene 10Peptidylprolyl isomerase A (cyclophilin A) pseudogenePeptidylprolyl isomerase A (cyclophilin A) pseudogene 10Peptidylprolyl isomerase A (cyclophilin A)-like 2
02

Mechanism of action

None documented (no drugs or molecular therapies target PPIAP10)

03

Biological functions

Possible *regulation of gene expression at the RNA level*, via microRNA competition*Other* (as a pseudogene, no direct protein-coding function)
04

Disease associations

Other (no documented direct disease role; Parental gene PPIA has disease associations, but PPIAP10 function not established in disease)

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