Peptidylprolyl isomerase A pseudogene 24 (PPIAP24)

Peptidylprolyl isomerase A pseudogene 24 (PPIAP24) is classified as a pseudogene related to the functional gene Peptidylprolyl isomerase A (PPIA, also known as cyclophilin A), but does not encode a functional protein product. Pseudogenes such as PPIAP24 are nonfunctional DNA sequences with high sequence similarity to a functional ancestral gene but lack protein-coding ability due to disablements like premature stop codons or frameshifts[2][8]. While some pseudogenes have been reported to play regulatory roles in gene expression, especially through RNA-based mechanisms (e.g., acting as decoys for microRNAs or generating siRNAs), there is no direct evidence in the literature that PPIAP24 has such functions or disease relevance[4][5][8]. As a result, PPIAP24 is not considered a therapeutic target or actionable molecular entity, and there is no information on drugs, biomarkers, mechanisms of action, or safety concerns specific to this pseudogene. The related functional gene, PPIA, is an enzyme involved in protein folding and has broad biological roles, but PPIAP24 itself should not be conflated with PPIA[1][9].\n\nNote: The information provided for "Peptidylprolyl isomerase A pseudogene 24" is very limited in public resources and scientific databases, and there is no evidence that PPIAP24 is functionally relevant or a drug target. If any claim refers to PPIA/Cyclophilin A or other PPIA pseudogenes with known function, that should not be transferred to PPIAP24 without direct evidence.