Peptidylprolyl isomerase A pseudogene 26 (PPIAP26)

Peptidylprolyl isomerase A pseudogene 26 (PPIAP26) is a human pseudogene associated with the peptidylprolyl isomerase A (PPIA, also known as cyclophilin A) gene family[1][6]. Pseudogenes are DNA sequences similar to known genes but typically nonfunctional as protein-coding genes. While some PPIA-related pseudogenes, such as PPIAP22, may exert regulatory effects through RNA mechanisms (for example, acting as competing endogenous RNAs), there is no specific functional or disease association reported for PPIAP26[5]. PPIAP26 does not produce a functional protein and is not considered a therapeutic target, receptor, or classical drug target. Any potential biological or clinical role would be indirect or speculated based on pseudogene or non-coding RNA regulatory functions, but this is unproven for PPIAP26. *Essential context:* - PPIAP26 should not be confused with peptidylprolyl isomerase A (PPIA, cyclophilin A), a catalytically active enzyme involved in protein folding, immune regulation, and HIV-1 replication, which is a genuine drug target[2][3][4]. - The information for PPIAP26 is minimal; most studies focus on the parental gene (PPIA) or other functionally relevant pseudogenes like PPIAP22[5]. If your use case requires an active protein target, consider searching for peptidylprolyl isomerase A (PPIA, cyclophilin A) rather than PPIAP26.

Other names

Peptidylprolyl isomerase A (cyclophilin A) pseudogene 26PPIAP26