Target intelligence / Profile preview

Peptidylprolyl isomerase A pseudogene 31 (PPIAP31)

Target
PPIAP31
Molecular classification
Pseudogene, Other
01

Overview

Peptidylprolyl isomerase A pseudogene 31 (PPIAP31) is a human pseudogene related to peptidylprolyl isomerase A (PPIA, cyclophilin A)[6][1]. Pseudogenes are DNA segments similar to functional genes but typically lack protein-coding ability due to disabling mutations[4]. Most pseudogenes do not encode active proteins but may sometimes have regulatory functions at the RNA level, such as acting as microRNA decoys or competitive endogenous RNAs in rare cases[2][4]. There is currently no evidence that PPIAP31 is involved in any specific biological function, disease, or therapeutic target activity.\n\nNote: PPIAP31 is distinct from PPIA, the functional protein involved in inflammation, apoptosis, cell signaling, and as a target of immunosuppressant cyclosporine[3][7]. If seeking information about a therapeutic target, refer to \"Peptidylprolyl isomerase A\" (PPIA/Cyclophilin A)[3][7].

Other names
Peptidylprolyl isomerase A pseudogene 31PPIAP31HGNC: 44962NCBI Gene: 439953Ensembl: ENSG00000217094
02

Mechanism of action

Not applicable (no known mechanism of action for drugs acting on PPIAP31)

03

Biological functions

No known direct biological function; pseudogenes can sometimes play regulatory roles via RNA (such as miRNA decoy or competitive endogenous RNA in a few cases, but no data for PPIAP31 specifically)
04

Disease associations

None described for PPIAP31Other pseudogenes in the PPIA family have regulatory effects in cancer (as competitive endogenous RNAs), but not PPIAP31 specifically
05

Safety considerations

None known
06

Interacting drugs

None (no drugs known to target PPIAP31)
07

Biomarkers

None known

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