Target intelligence / Profile preview

Peptidylprolyl isomerase A pseudogene 35 (PPIAP35)

Target
PPIAP35
Molecular classification
Other (Pseudogene), Long non-coding RNA (lncRNA, inferred by analogy to related PPIA pseudogenes)
01

Overview

Peptidylprolyl isomerase A pseudogene 35 (PPIAP35) is a non-coding genomic locus classified as a pseudogene—a DNA sequence similar to the functional peptidylprolyl isomerase A (PPIA) gene, but lacking protein-coding potential and functional activity[7][3]. Like other pseudogenes, PPIAP35 may be transcribed into non-coding RNA, but there is no evidence that it produces an active protein or serves as a molecular drug target. Some PPIA-related pseudogenes are reported to regulate their parental gene by acting as competing endogenous RNAs (ceRNAs), but specific functional annotation or disease association for PPIAP35 is currently not established[4][6]. Key points: - PPIAP35 is a pseudogene, not a protein-coding gene[7][3]. - Not a therapeutic target, receptor, enzyme, or transporter. - No known drugs, mechanisms of action, or biomarker roles. - No clinical or pharmacological utility reported. - If you require information about the functional enzyme "Peptidylprolyl isomerase A" (PPIA, also called cyclophilin A), refer specifically to the PPIA gene and protein, not the pseudogene PPIAP35[8].

Other names
NCBI Gene ID: 128192
02

Biological functions

Possible regulation of parental gene (by RNA mechanisms; inferred from related pseudogenes)Other (Pseudogenes can act as regulatory non-coding RNAs in some contexts, but specific function for PPIAP35 is not reported)
03

Disease associations

Other (Direct evidence for PPIAP35 in disease is currently lacking. Related PPIA pseudogenes have been implicated in gene regulatory networks.)

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