Target intelligence / Profile preview

Peptidylprolyl isomerase A pseudogene 46 (PPIAP46)

Target
PPIAP46
Molecular classification
Other (Pseudogene)
01

Overview

PPIAP46 is a pseudogene related to the peptidylprolyl isomerase A (PPIA, cyclophilin A) gene family. Pseudogenes are genomic DNA sequences similar to normal genes but are non-functional due to mutations or lack of regulatory elements that prevent protein expression[3][9]. While some pseudogenes can participate in regulating gene expression (for example, by acting as microRNA decoys or being transcribed into non-coding RNA with potential regulatory functions), there is no direct evidence that PPIAP46 plays such roles. Importantly, PPIAP46 does not code for an active enzyme or receptor and is not considered a molecular target for drugs or therapeutic intervention. If information about biological function, disease relevance, or interactions is needed for "peptidylprolyl isomerase A" (PPIA, cyclophilin A), consult the literature on PPIA, not pseudogenes like PPIAP46[3][9].

Other names
Peptidylprolyl isomerase A pseudogene 46PPIAP46Peptidylprolyl isomerase A (cyclophilin A) pseudogene, PPIAP46
02

Biological functions

Other (pseudogenes typically do not encode proteins but may have regulatory functions such as acting as microRNA "decoys" or being involved in RNA-based regulation[3][6])
03

Disease associations

Other (Some pseudogenes, in general, have been implicated in cancer or regulating tumor suppressors through RNA-mediated mechanisms, but no evidence is available for PPIAP46 specifically[3][6])

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