Peptidylprolyl isomerase A pseudogene 48 (PPIAP48)

Peptidylprolyl isomerase A pseudogene 48 (PPIAP48) is classified as a pseudogene, meaning it is a genomic DNA sequence similar to that of the functional peptidylprolyl isomerase A gene (PPIA), but it is not believed to encode an active protein product. Pseudogenes typically arise through gene duplication or retrotransposition events and usually accumulate disabling mutations, so they do not have the molecular or biological functions found in protein-coding genes. PPIAP48 is not known to have any therapeutic relevance as a drug or biomarker target, and there is no evidence linking it to disease mechanisms or drug interactions. Its inclusion as a target is incorrect because pseudogenes are not recognized as conventional targets (such as receptors, enzymes, transporters, etc.) for drug therapy. This designation should be flagged as potentially incorrect if included among functional therapeutic targets.

Other names

PPIAP48