Peptidylprolyl isomerase A pseudogene 58 (PPIAP58)

Peptidylprolyl isomerase A pseudogene 58 (PPIAP58) is a pseudogene related to peptidylprolyl isomerase A (cyclophilin A)[7]. Unlike the protein-coding gene PPIA (which encodes cyclophilin A, a peptidyl-prolyl cis-trans isomerase involved in protein folding, immune response, and viral infection), PPIAP58 does not encode a functional protein and does not participate directly in biological signaling or disease progression. While other pseudogenes of PPIA have been implicated in non-coding RNA–mediated regulation of the parent gene in cancer[8], there is no evidence that PPIAP58 itself has such a role. It is not considered a therapeutic target, and no drugs are described that act on it. Key distinction: - PPIAP58 is a pseudogene, not a functional gene, receptor, or enzyme. - Do not confuse PPIAP58 (the pseudogene) with PPIA (Cyclophilin A), which is a well-characterized drug target with roles in immunity and infection[2][3]. If you need information about Cyclophilin A (PPIA) as a therapeutic target, refer specifically to "Peptidylprolyl isomerase A (Cyclophilin A)" or "PPIA" rather than pseudogenes like PPIAP58[3][7].

Other names

Peptidylprolyl isomerase A (cyclophilin A) pseudogenePPIAP58