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Target intelligence / Profile preview
Peptidylprolyl isomerase A pseudogene 6 (PPIAP6)
- Target
- PPIAP6
- Molecular classification
- Other (pseudogene; not classified as enzyme, receptor, transporter, or ion channel)
01
Overview
Peptidylprolyl isomerase A pseudogene 6 is a human pseudogene related to the functional enzyme peptidylprolyl isomerase A (PPIA), which catalyzes the cis-trans isomerization of proline imidic peptide bonds in proteins. Unlike PPIA, PPIAP6 does not encode a functional protein and is considered non-coding. In general, pseudogenes arise from duplication or retrotransposition events and accumulate mutations that prevent proper translation or protein function. While some pseudogenes may influence gene regulation by acting as competing endogenous RNAs (ceRNAs) or affecting parental gene expression through microRNAs, there are no published data supporting a functional or disease regulatory role for PPIAP6 specifically[3][2][6]. PPIAP6 has no recognized molecular function, biological process, or involvement in disease pathways, and it is not a pharmacological target.
- Other names
- PPIAP12PPIP2
02
Mechanism of action
None (no drugs target this pseudogene)
03
Biological functions
None established (pseudogenes generally do not produce functional proteins; however, some pseudogenes might regulate their parent gene's expression or participate in non-coding RNA functions)
04
Disease associations
Other (no direct disease association established for PPIAP6; other PPIA pseudogenes such as PPIAP22 may regulate cancer pathways, but there is no data for PPIAP6)
05
Safety considerations
None (not therapeutically targeted, so no safety concerns apply)
06
Interacting drugs
None (pseudogenes are not drug targets)
07
Biomarkers
None (not used for patient selection or efficacy monitoring)
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