Peptidylprolyl isomerase A pseudogene 65 (PPIAP65)

Peptidylprolyl isomerase A pseudogene 65 (PPIAP65) is a pseudogene in the human genome. It is one of multiple pseudogenes that share high sequence similarity with the peptidylprolyl isomerase A (PPIA) gene, but it does not produce a functional protein and has no described biological or pathological functions. As a pseudogene, PPIAP65 is not considered a molecular target for therapy, does not interact with drugs, and is not known to function as a biomarker. Current gene databases do not ascribe it any clinical or biological significance beyond its sequence similarity to PPIA[2][6]. To clarify: PPIAP65 is distinct from the protein-coding PPIA (Peptidylprolyl isomerase A/cyclophilin A) gene, which encodes an enzyme involved in protein folding, signaling, and is a target of the immunosuppressant cyclosporin, with well-defined disease roles and drug interactions[1][2]. By contrast, PPIAP65 is an inactive pseudogene with no such roles.

Other names

PPIAP65