Peptidylprolyl isomerase A pseudogene 67 (PPIAP67)

Peptidylprolyl isomerase A pseudogene 67 (PPIAP67) is designated as a pseudogene related to the parental gene *peptidylprolyl isomerase A* (PPIA)[2][3]. Pseudogenes are DNA sequences similar to known genes but have lost their protein-coding potential due to mutations; they do not encode functional proteins and are not considered direct therapeutic targets such as receptors, enzymes, or transporters. While some pseudogenes may act as non-coding RNAs that regulate the expression of their parental gene or serve as competing endogenous RNAs in specific contexts (e.g., PPIAP22[3], PPIAP43[2]), there is currently no evidence that PPIAP67 has functional biological activity, disease associations, or drug interactions. There are no approved drugs or known mechanisms of action involving PPIAP67. Therefore, PPIAP67 is not considered a classical molecular target. Key clarifications: - The "is_target" field is **false** for PPIAP67, as it is not a functional receptor, enzyme, or therapeutic target. - The "is_incorrect" field is **true**, as PPIAP67 is sometimes mistakenly listed among targets due to confusion with the functional parent gene *PPIA* (cyclophilin A)[1][2][3]. If you are seeking a therapeutic target, you should refer to *peptidylprolyl isomerase A* (PPIA or cyclophilin A), not its pseudogenes. - For all functional and disease-relevant information, consult literature on *peptidylprolyl isomerase A* (PPIA), not its pseudogenes except in rare regulatory RNA contexts, which do not apply to PPIAP67 based on current data[2][3].

Other names

PPIAP67