Peptidylprolyl isomerase A pseudogene 77 (PPIAP77)

Peptidylprolyl isomerase A pseudogene 77 (PPIAP77) is a human pseudogene related to the parental gene peptidylprolyl isomerase A (PPIA, also known as cyclophilin A). Pseudogenes such as PPIAP77 are classified as genomic DNA sequences similar to known genes but generally lack the ability to encode proteins due to mutations or deletions disrupting their coding potential. There are no known reports of PPIAP77 acting as a therapeutic target, biomarker, or being functionally implicated in human disease or physiology. This is distinct from other pseudogenes of PPIA such as PPIAP22, for which some regulatory roles have been suggested in disease, but no such roles or functions have been attributed to PPIAP77. The only information available from referenced gene and genomics databases indicates that PPIAP77 is annotated as a "pseudogene" for PPIA in humans, without functional characterization or recognized clinical or therapeutic relevance. There is no evidence that it encodes a protein or has any direct drug interactions, mechanisms of action, biomarker value, or safety concerns; pseudogenes typically do not produce functional proteins. The scientific literature does not currently report any biological, regulatory, or disease-related significance for this specific pseudogene (PPIAP77). In summary, PPIAP77 is a non-coding pseudogene corresponding to peptidylprolyl isomerase A, with no established biological, clinical, or therapeutic functions.

Other names

PPIA pseudogene 77