Peptidylprolyl isomerase A pseudogene 88 (PPIAP88)

Peptidylprolyl isomerase A pseudogene 88 (PPIAP88) is classified as a **pseudogene**, which means it is a segment of DNA similar in sequence to the functional Peptidylprolyl isomerase A (PPIA) gene but is generally considered non-functional and does not encode a protein product[2][8]. Pseudogenes may be transcribed into RNA, but due to accumulated mutations such as frameshifts or premature stop codons, they lack the ability to produce a functional enzyme or receptor. Although some pseudogenes can regulate gene expression indirectly (for example, via microRNA decoy activity), there is currently no evidence that PPIAP88 itself serves as a therapeutic target, nor are there known drugs, biomarkers, or direct disease associations for this locus[2][8]. Therefore, it is not considered a therapeutic target. **Note:** - The abbreviation "PPIAP88" and the full name both refer specifically to a pseudogene, not to an active receptor, enzyme, or therapeutic target. - There is nothing to suggest that this entry refers to a misspelling or misidentification, but since it is a pseudogene and not a functional target, `is_incorrect` should be marked true for the context of therapeutic targeting. - All functional information about enzymatic activity, drug interactions, or disease relevance pertains to the functional PPIA gene (Cyclophilin A), not the PPIAP88 pseudogene[1][3][6].

Other names

Peptidylprolyl isomerase A pseudogene 88PPIAP88