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Peptidylprolyl isomerase A pseudogene 90 (PPIAP90) is classified as a pseudogene of peptidylprolyl isomerase A and lacks evidence of protein-coding function or enzymatic/receptor activity[2]. Pseudogenes generally do not encode functional proteins or act as direct therapeutic targets in drug development. Some pseudogenes of peptidylprolyl isomerase A, such as PPIAP22, are reported to function as regulatory long non-coding RNAs involved in cancer biology, but there is currently no published data about any functional role or disease association for PPIAP90 specifically[2]. No common disease roles, biomarkers, or clinically relevant drug interactions have been described for PPIAP90. Therefore, PPIAP90 is not considered a therapeutic target, and its listing as a drug target is likely incorrect or based on a misunderstanding of its function[2][3].
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