Peptidylprolyl isomerase A pseudogene 91 (PPIAP91)

Peptidylprolyl isomerase A pseudogene 91 (PPIAP91) is a processed pseudogene related to the functional gene peptidylprolyl isomerase A (PPIA), which encodes the enzyme cyclophilin A. PPIAP91 does not encode a functional protein and is classified as a pseudogene, meaning it arises from gene duplication or retrotransposition events, but has lost the ability to code for a protein product[3]. While some pseudogenes can act as regulatory long non-coding RNAs—impacting gene expression through various RNA-mediated mechanisms—there is no direct scientific evidence in the current literature that PPIAP91 has a known biological function, role in disease, or any value as a therapeutic target, biomarker, or drug-interacting molecule[3]. The confusion often arises because closely related pseudogenes, such as PPIAP22, have been reported in research to modulate cancer biology as long non-coding RNAs, but no such data exists for PPIAP91 specifically[4][7].

Other names

Peptidylprolyl isomerase A pseudogene 91PPIAP91

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