Target intelligence / Profile preview

Peripheral Artery (None)

Target
None
Molecular classification
Blood vessel
01

Overview

Peripheral arteries are blood vessels that transport oxygenated, nutrient-rich blood from the heart to the organs and tissues located outside of the central thoracic area, primarily supplying the arms, legs, hands, and feet. Peripheral artery is not a single molecule/receptor but rather refers collectively to all major systemic arteries outside of coronary/cerebral circulation. In clinical research contexts related specifically to "target molecules," focus may shift toward molecular mediators involved in arterial health/disease such as endothelial cells expressing VEGF-A165 or smooth muscle cells targeted by regenerative therapies for PAD patients.

02

Mechanism of action

Improving arterial perfusion through lifestyle changes, medications, and/or procedures.

03

Biological functions

Deliver oxygenated blood to extremitiesTissue perfusion
04

Disease associations

Peripheral Artery Disease (PAD)Cardiovascular disease
05

Safety considerations

Risk of heart attack/strokeCritical limb ischemiaAmputation
06

Interacting drugs

Antiplatelet agents

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