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Target intelligence / Profile preview
Peripheral blood stem cell (PBSC) (PBSC)
- Target
- PBSC
- Molecular classification
- Hematopoietic stem cell, Progenitor cell
01
Overview
Donor-derived PBSCs are collected for transplantation to support engraftment and hematopoiesis, not representing a single molecule but a therapeutic cell product essential for HSCT.[1][3]
- Other names
- Peripheral blood stem celldonor-derived PBSChematopoietic progenitor cell
02
Mechanism of action
Mobilization; Immune modulation
03
Biological functions
HematopoiesisEngraftmentImmune reconstitutionBone marrow reconstitution
04
Disease associations
Bone marrow failureHematologic malignancyGenetic disorderImmune system disorder
05
Safety considerations
Graft-versus-host diseaseGraft failureInfection riskInfusion reactions
06
Interacting drugs
Granulocyte colony-stimulating factor (G-CSF)
2 more in the full profile.
07
Biomarkers
CD34+ cell countChimerism analysis
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