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"Peristalsis stimulation via increased fecal mass" refers to the initiation or enhancement of peristaltic contractions in the gastrointestinal tract as a response to increased volume or bulk of intestinal contents. This increased mass stretches the walls of the colon and rectum, activating stretch-sensitive enteric nerves and triggering the peristaltic reflex, which propels fecal material toward the anus, facilitating defecation[3][5][7]. Clinically, this mechanism underlies the action of many bulk-forming or osmotic laxatives used to manage constipation.
Increases fecal mass, stimulating stretch receptors in the colonic wall, which in turn triggers peristaltic reflexes via the enteric nervous system, promoting bowel movement[3][4][5][7][9].
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