Peroxiredoxin 3 pseudogene

**Peroxiredoxin 3 pseudogene (ENSG00000270690)** is a nonfunctional DNA segment in the human genome that shares significant sequence homology with the functional *peroxiredoxin 3* gene (PRDX3) but contains disabling mutations that prevent it from encoding a functional protein. Pseudogenes like this one arise as duplications or retrotransposed copies of functional genes but lack regulatory elements or contain frameshifts, stop codons, or other mutations that render them incapable of proper transcription, translation, or protein production[1][2][6][8]. While some pseudogenes may influence gene regulation in rare cases, the peroxiredoxin 3 pseudogene has no established biological function, no known role in disease, and is not considered a therapeutic target[1][2][5][6]. Its nomenclature reflects its relationship to the antioxidant enzyme peroxiredoxin 3 (PRDX3), but it does not produce this protein nor has any known physiological or pathological effect. Additional details: - If you seek the functional protein, refer to the *peroxiredoxin 3* gene (PRDX3, ENSG00000165672)[4][9]. - The presence of pseudogenes can sometimes complicate PCR assays or genomic studies as they may be inadvertently amplified along with their parental genes[1]. - Pseudogenes are not typically classified in canonical molecular families such as "enzyme", "receptor", or "transcription factor", as they do not produce active gene products[1][2]. - No synonyms or common drug interaction data exist for this locus, and it is frequently omitted from structured pharmacological or biomarker databases. Summary: This entry is a **pseudogene** and not a protein-coding gene, validated drug target, or receptor/enzyme/transporter. It does not have unique aliases or abbreviation, nor established disease roles or drug interactions, and is primarily a nonfunctional genomic artifact[1][2][6][8].

Other names

PRDX3 pseudogeneperoxiredoxin 3 pseudogene (suffix index varies by annotation)