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The peroxiredoxin 5 pseudogene is a genomic sequence that resembles the peroxiredoxin 5 gene but does not code for a functional protein due to mutations disrupting its coding potential[1][3]. Pseudogenes like this can arise through gene duplication, retrotransposition, or gene-inactivating mutations[1][4]. Most pseudogenes, including this one, do not have known functional roles in human biology, though a minority across the genome may exert some regulatory influence at the RNA level[2][4]. There is no evidence this pseudogene encodes any protein or is druggable, and it is not considered a therapeutic target. In summary, "peroxiredoxin 5 pseudogene" (ENSG00000223428) is an **inactive gene copy**, not a druggable or functional therapeutic target. Its entry in any structured target database should be flagged as incorrect for use in therapeutic or drug-targeting contexts.
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