Peroxiredoxin 6 pseudogene (PRDX6P)

The peroxiredoxin 6 pseudogene (ENSG00000213331) is a processed pseudogene—a nonfunctional segment of DNA that shares sequence similarity with the peroxiredoxin 6 gene, a gene involved in antioxidant defense. Processed pseudogenes arise by retrotransposition events and lack the necessary regulatory elements or intact coding sequence for protein expression. While some pseudogenes can be transcribed to RNA and may rarely play regulatory roles, there is no substantial evidence that ENSG00000213331 is functional, nor does it act as a therapeutic target or participate in disease mechanisms[1][2][5]. Pseudogenes are typically "junk DNA"—remnants of genes that have lost function due to mutation or duplication events. Most are not transcribed, but some can influence expression of other genes via regulatory RNAs[1][2][4]. ENSG00000213331 specifically refers to a processed pseudogene related to peroxiredoxin 6; no evidence is available to suggest it produces protein, interacts with drugs, or acts as a biomarker[5]. There is no indication this pseudogene is misclassified; pseudogenes are commonly annotated in genomic databases and should not be confused with functional therapeutic targets[3].

Other names

PRDX6Pprocessed peroxiredoxin 6 pseudogene

None, as no drugs target this molecule directly.