Target intelligence / Profile preview

Peroxiredoxin like 2A pseudogene 1 (PRXL2AP1)

Target
PRXL2AP1
Molecular classification
Other (Pseudogene)
01

Overview

**Peroxiredoxin like 2A pseudogene 1 (PRXL2AP1)** is a human pseudogene related by sequence homology to the peroxiredoxin-like 2A family, but is classified as a pseudogene, meaning it does not encode a functional protein. There is no evidence it acts as a receptor, enzyme, transporter, or classical therapeutic target. Pseudogenes can sometimes have regulatory functions at the RNA level, such as acting as miRNA decoys or influencing related gene expression, but no such functional association has been characterized for PRXL2AP1 specifically. The gene is annotated principally as a unit of genetic sequence without any confirmed biological or pathophysiological function[2][5][6]. **Notes:** - This gene is **not considered an actionable therapeutic target**. It is a pseudogene—not a protein-coding gene, receptor, enzyme, or other molecular target[2]. - There is no evidence that PRXL2AP1 contributes to any disease as a driver or biomarker, nor that any drugs interact with it or target it. - The entry is correct in name and general category, but it is "incorrect" as a molecular target in drug discovery or therapeutic context (not a receptor, not "druggable," not a driver of disease) and should be annotated accordingly. If you need information about the functional/coding gene, refer to PRXL2A (Peroxiredoxin like 2A, also known as FAM213A/Adiporedoxin)[7].

Other names
FAM213AP1family with sequence similarity 213 member A pseudogene 1PRXL2AP1
02

Biological functions

Other (no known protein function; pseudogene)
03

Disease associations

Other (no direct association or function established; see below)

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