Pescadillo ribosomal biogenesis factor 1 pseudogene 2 (PES1P2)

Pescadillo ribosomal biogenesis factor 1 pseudogene 2 (PES1P2) is a genomic element classified as a pseudogene, meaning it is a copy of the PES1 gene that has lost its protein-coding ability and is considered non-functional as a protein-coding gene[1][3]. The PES1 gene encodes a protein involved in ribosome biogenesis and cell proliferation, and plays a role in cancer biology[5][7]; however, PES1P2 itself does not produce a functional protein and has not been linked directly to any therapeutic function, disease implication, or use as a clinical target[1][3]. There is no validated evidence of clinical utility, drug interactions, or efficacy/safety biomarker status for PES1P2. As with many pseudogenes, it may be transcribed as a long non-coding RNA, but specific roles have not been described for PES1P2 itself as distinct from other pseudogenes[1][3][4]. No evidence in the scientific literature indicates that PES1P2 is a therapeutic or druggable target, nor is it implicated as a biomarker or safety concern. All available data classify it as a non-functional pseudogene related to PES1, which itself is a ribosomal biogenesis factor relevant in cancer pathways, but PES1P2 does not share these functions[1][3][7].

Other names

RP11-284P20.2PES1P2