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Phlegm resolution via multiple botanical actions according to TCM theory describes a therapeutic strategy in Traditional Chinese Medicine that aims to eliminate pathological "phlegm"—a concept not limited to mucus but referring broadly to deleterious accumulations resulting from imbalances such as spleen deficiency and dampness. This approach typically involves multi-herbal formulas and may combine heated (Qi-moving) and dampness-clearing botanicals, often targeting respiratory and immune functions, modulating inflammation, and improving airway mucus clearance. The underlying mechanisms, as interpreted in modern pharmacological terms, include inhibition of inflammatory cytokines, regulation of mucin expression, and immunomodulatory effects, but there is no corresponding molecular receptor, enzyme, or transporter. This is a conceptual therapeutic method, not a discrete molecular target, and should not be treated as a receptor or protein.
Inhibition of inflammation-related cytokines and adhesion molecules Modulating airway mucus hypersecretion (Mucin-family, via MAPK and cytokine-related pathways) Strengthening spleen and lung function Regulating Qi and dampness Modulation of immune function (e.g., through NF-κB or JAK-STAT pathways) Clearing "heat" and reducing "phlegm" (specific to TCM framework)
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