Drug pipeline
Full profile accessExplore the programs pursuing this target and their development progress.
- Drug candidates
- Developers
- Development stage
Target intelligence / Profile preview
Phosphatase and actin regulator 2 (PHACTR2)
- Target
- PHACTR2
- Molecular classification
- Other (regulatory protein, actin regulator), Phosphatase modulator
01
Overview
Phosphatase and actin regulator 2 (PHACTR2) is a human protein functioning primarily as a modulator of protein phosphatase activity and actin cytoskeleton organization. It is predicted to enable actin binding and protein phosphatase inhibitor activity, influencing cell shape, migration, and cytoskeletal dynamics. PHACTR2 is implicated in several pathways relevant to cell signaling and structure, and is associated with neurological diseases such as Parkinson’s disease, multiple sclerosis, and has been cited as a biomarker for Alzheimer’s disease. Diseases directly associated with mutations in the gene include body dysmorphic disorder and lissencephaly 8. PHACTR2 is ubiquitously expressed, and no drugs are known to target or interact with this protein; it is not a therapeutic receptor, enzyme, transporter, or transcription factor[3][4][10][11].
- Other names
- C6orf56KIAA0680
02
Biological functions
Actin bindingActin cytoskeleton organizationProtein phosphatase inhibitor activity
03
Disease associations
Neurodegenerative disease (Parkinson’s disease, Alzheimer’s disease, Multiple sclerosis)Body dysmorphic disorderLissencephaly 8
04
Biomarkers
Alzheimer's disease (proposed biomarker)broader CNS disease biomarker potential
Beyond the preview
Go deeper on Phosphatase and actin regulator 2 (PHACTR2).
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Clinical trials
Full profile accessFollow the clinical studies evaluating therapies directed at this target.
- Trial design
- Status
- Readouts
Competitive landscape
Full profile accessCompare approaches across drug candidates, modalities, and indications.
- Programs
- Modalities
- Indications
Literature & evidence
Full profile accessInvestigate the research and source evidence behind target biology and development.
- Publications
- Sources
- Analysis
Patents
Full profile accessExplore patent activity around therapies and technologies addressing this target.
- Patents
- Assignees
- Technologies
Research & analysis
Full profile accessConnect target biology, drug development, and emerging evidence in your research.
- Biology
- Development news
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on Phosphatase and actin regulator 2 (PHACTR2).