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Phosphatidylcholine (PC)

Target: PC
Molecular classification: Glycerophospholipid, Phospholipid

Overview

Phosphatidylcholine (PC) is a class of phospholipids characterized by a choline headgroup. It is a major structural component of eukaryotic cell membranes, contributing to membrane integrity, fluidity, and function. PC is also a key component of pulmonary surfactant and plays roles in lipid transport and cell signaling. While often used synonymously with lecithin, lecithin is a mixture of phospholipids including PC. PC is investigated for various medical uses, including brain health, liver support, and cholesterol management, although the evidence supporting these uses varies.

Other names: LecithinPtdCho

Mechanism of action

N/A

Biological functions

Membrane structureMembrane functionCell signalingLipid transportPulmonary surfactant component

Disease associations

Memory lossAlzheimer's diseaseLiver diseaseHigh cholesterolFat embolism

Safety considerations

Variable composition of lecithin extractsPotential for solvent residues from extraction (e.g., hexane)Insufficient evidence for some claimed therapeutic benefits

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