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Target intelligence / Profile preview
Phosphatidylinositol 4-kinase (PI4K)
- Target
- PI4K
- Molecular classification
- Lipid Kinase, Enzyme
01
Overview
Phosphatidylinositol 4-kinase refers collectively to several related enzymes essential for producing key lipid signaling molecules that define organelle identity, regulate intracellular transport pathways, support neuronal/synaptic function, enable pathogen replication platforms—and represent promising drug targets across virology/parasitology/cancer biology fields.
- Other names
- PI4-kinasePhosphatidylinositol 4-kinases
02
Mechanism of action
Inhibition of phosphatidylinositol 4-kinase activity
03
Biological functions
Phosphorylation of phosphatidylinositolLipid signalingMembrane identityVesicular traffickingRegulation of Golgi and trans-Golgi network membranesRegulation of membrane curvature
04
Disease associations
NeurodegenerationCancerViral infectionMalaria
05
Interacting drugs
PI4K inhibitors
1 more in the full profile.
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