Phosphatidylinositol binding clathrin assembly protein pseudogene

The "phosphatidylinositol binding clathrin assembly protein pseudogene" is a non-coding DNA sequence in the human genome that resembles the functional PICALM gene but is nonfunctional and does not encode a protein[2][8][5]. Pseudogenes such as this one are generally considered genomic "fossils": they arise through duplication or retrotransposition and lose the ability to code for functional protein, although some may be transcribed at low levels or have rare regulatory roles[2][5]. This specific pseudogene is not a receptor, enzyme, transporter, or other therapeutic target, and it does not possess the biological functions, interactions, or clinical significance of the parent gene. All associations with disease, biological function, or drug interaction apply to the functional PICALM gene, not its pseudogenes[2][4][7].

Other names

PICALM pseudogenephosphatidylinositol-binding clathrin assembly protein pseudogenePICALM-psi