Drug pipeline
Full profile accessExplore the programs pursuing this target and their development progress.
- Drug candidates
- Developers
- Development stage
Target intelligence / Profile preview
Phosphodiesterase 7A (None)
- Target
- None
- Molecular classification
- Enzyme, cAMP-specific phosphodiesterase
01
Overview
Phosphodiesterase 7A (PDE7A) is a high-affinity, cAMP-specific 3',5'-cyclic phosphodiesterase enzyme. By controlling cAMP levels, it plays a key role in modulating cellular responses to various stimuli. It is highly expressed in immune cells such as T lymphocytes and several brain regions. Research suggests that selective inhibitors targeting PDE7 could be beneficial for treating autoimmune diseases mediated by T cells as well as central nervous system disorders such as Parkinson's disease and Alzheimer's disease due to its regulatory role on neuronal survival pathways via cAMP signaling modulation.
- Other names
- HCP1PDE7
02
Mechanism of action
Selective inhibition of PDE7A leads to increased intracellular cAMP levels.
03
Biological functions
Hydrolysis of cAMPRegulation of immune responseNeuronal signaling
04
Disease associations
Chronic lymphocytic leukemiaMicrophthalmiaNeurodegenerative diseaseAutoimmune disease
Beyond the preview
Go deeper on Phosphodiesterase 7A (None).
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Clinical trials
Full profile accessFollow the clinical studies evaluating therapies directed at this target.
- Trial design
- Status
- Readouts
Competitive landscape
Full profile accessCompare approaches across drug candidates, modalities, and indications.
- Programs
- Modalities
- Indications
Literature & evidence
Full profile accessInvestigate the research and source evidence behind target biology and development.
- Publications
- Sources
- Analysis
Patents
Full profile accessExplore patent activity around therapies and technologies addressing this target.
- Patents
- Assignees
- Technologies
Research & analysis
Full profile accessConnect target biology, drug development, and emerging evidence in your research.
- Biology
- Development news
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on Phosphodiesterase 7A (None).