Target intelligence / Profile preview

Phosphoglucomutase 5 pseudogene 2 (PGM5P2)

Target
PGM5P2
Molecular classification
Pseudogene, Long noncoding RNA (lncRNA), Other (noncoding RNA)
01

Overview

Phosphoglucomutase 5 pseudogene 2 (PGM5P2) is a noncoding RNA annotated as a pseudogene. It does not code for a functional protein but is implicated in the regulation of biological processes relevant to cancer. Increased expression of PGM5P2 is correlated with better prognosis in certain cancers, such as lung adenocarcinoma and breast cancer, suggesting potential tumor-suppressive activities, including pro-apoptosis and antiangiogenesis. The precise molecular function and regulatory mechanisms of PGM5P2 remain unclear, and further research is required. While PGM5P2 may serve as a biomarker within prognostic gene signatures, it is not considered a classic therapeutic target like a receptor, enzyme, or transporter[1][2]. PGM5P2 is primarily referenced in molecular profiling studies, such as support vector machine (SVM) classifiers for disease prognosis, and has not been linked to direct pharmacological interventions or traditional therapeutic modalities[1][2].

Other names
AK096159
02

Biological functions

Putative pro-apoptosis activityPutative antiangiogenesis processCandidate tumor suppressor function in lung adenocarcinoma (LUAD) and breast cancerPossible association with immune response and cancer progression
03

Disease associations

Cancer (notably lung adenocarcinoma and possibly breast cancer)Possible involvement in pathways relevant to tumor progression and immune response
04

Biomarkers

PGM5P2 expression has been used as part of multigene prognostic signatures for lung and breast cancer, indicating association with better prognosis when upregulated

Beyond the preview

Go deeper on Phosphoglucomutase 5 pseudogene 2 (PGM5P2).

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Drug pipeline

Full profile access

Explore the programs pursuing this target and their development progress.

  • Drug candidates
  • Developers
  • Development stage

Clinical trials

Full profile access

Follow the clinical studies evaluating therapies directed at this target.

  • Trial design
  • Status
  • Readouts

Competitive landscape

Full profile access

Compare approaches across drug candidates, modalities, and indications.

  • Programs
  • Modalities
  • Indications

Literature & evidence

Full profile access

Investigate the research and source evidence behind target biology and development.

  • Publications
  • Sources
  • Analysis

Patents

Full profile access

Explore patent activity around therapies and technologies addressing this target.

  • Patents
  • Assignees
  • Technologies

Research & analysis

Full profile access

Connect target biology, drug development, and emerging evidence in your research.

  • Biology
  • Development news
  • Analysis

Bring the full picture into focus.

See how Gosset can support your research on Phosphoglucomutase 5 pseudogene 2 (PGM5P2).

Explore the full profile

Gosset Free

Get started with Gosset.

Enter your work email and we’ll be in touch with next steps.

Work email preferred.

Book a call