Phosphoglycerate mutase 1 pseudogene (PGAM1P1)

Phosphoglycerate mutase 1 pseudogene encodes a non-functional, processed pseudogene of the phosphoglycerate mutase 1 gene. It arose from retrotransposition of PGAM1 mRNA and has features typical of processed pseudogenes, such as high sequence similarity to its parent gene and lack of introns. It is located within the Menkes disease gene (ATP7A) on the X chromosome, but has not been detected as expressed in human tissues and has no known protein-coding function. This pseudogene is sometimes incorrectly referenced in the context of drug targets or disease biology, but it should not be confused with the functional metabolic enzyme PGAM1. Key distinctions: PGAM1P1 (the pseudogene) is NOT to be confused with PGAM1 (the enzyme), which is a target in oncology and metabolism research. The pseudogene is non-functional and there is no evidence it plays a role in disease or has interactions with drugs designed to modulate glycolysis or cancer cell proliferation.

Other names

PGAM1P1Phosphoglycerate mutase 1 pseudogene 1

None applicable. Mechanisms described for PGAM1 (e.g., glycolysis inhibition, cancer cell proliferation attenuation) do not apply to the pseudogene