Phosphoglycerate mutase 1 pseudogene 10 (PGAM1P10)

Phosphoglycerate mutase 1 pseudogene 10 (PGAM1P10) is a genomic DNA sequence classified as a pseudogene because it resembles the PGAM1 gene but contains sequence alterations that prevent it from producing a functional protein. Pseudogenes do not encode active proteins and typically lack biological function. Most available research and therapeutic attention is directed at functional PGAM1, an enzyme involved in glycolysis that is overexpressed in some cancers and is considered a potential anticancer target[1][2][3]. There is no evidence that PGAM1P10 has any role in disease, drug interaction, biomarker utility, or safety concerns, and it is not a molecular target for drugs or therapeutic interventions. If your query concerns the functional human enzyme "phosphoglycerate mutase 1" (PGAM1), please clarify, as this is a well-described glycolytic enzyme and bona fide oncology target, unrelated to the pseudogene PGAM1P10[1][2][3].

Other names

PGAM1 pseudogene 10