Phospholipid scramblase family member 5 (PLSCR5)

Phospholipid scramblase family member 5 (PLSCR5) is a predicted protein in humans encoded by the PLSCR5 gene on chromosome 3q24[1][3][4]. It is believed to enable phospholipid scramblase activity, facilitating the bidirectional movement of phospholipids between the inner and outer leaflets of cell membranes, a process known as phospholipid scrambling[1][4][7]. While PLSCR5 is part of the phospholipid scramblase family, including PLSCR1, its specific physiological functions, substrate preference, and biological roles remain largely uncharacterized and are inferred primarily by homology and expression data[1][2][3][4]. No significant direct evidence exists for PLSCR5 as a therapeutic drug target, nor are there known interacting drugs or clinical biomarkers as of current data. Genetic association data have suggested a possible link between PLSCR5 and visceral fat distribution in humans, but its functional or pathological significance in disease remains uncertain[1].

Other names

PLSCR5phospholipid scramblase family, member 5PLS5_HUMAN