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Phosphomannomutase 2 pseudogene 1 (PMM2P1)

Target: PMM2P1
Molecular classification: Other (Pseudogene; not an enzyme, receptor, transporter, transcription factor, etc.)

Overview

Phosphomannomutase 2 pseudogene 1 (PMM2P1) is a nonfunctional, processed pseudogene located on chromosome 18p in the human genome. It arose by duplication from the active gene phosphomannomutase 2 (PMM2) and retains high sequence similarity to PMM2 but does not produce a functional protein or participate in any known biological pathways. Several mutations found in the disease-associated PMM2 gene are also present in PMM2P1, reflecting its close evolutionary history. No diseases have been associated with defects in PMM2P1, nor is it relevant as a therapeutic target, biomarker, or drug interaction partner. If a query refers to PMM2P1 as a target, it is incorrect: the functional, disease-relevant target is PMM2 (phosphomannomutase 2).

Other names: PMM2psiPMM2 pseudogene

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