Phosphoribosyl pyrophosphate synthetase pseudogene

The phosphoribosyl pyrophosphate synthetase pseudogene is a genetic element similar in sequence to the protein-coding PRPS genes, but is classified as a pseudogene, meaning it does not encode a functional protein and is not expressed as an active enzyme. Pseudogenes are remnants of once-functional genes that have lost their protein-coding ability or are otherwise non-functional due to mutations. This pseudogene does not contribute to cellular metabolism or disease processes directly. Its functional relatives, such as PRPS1 and PRPS2, are enzymes involved in nucleotide biosynthesis and purine metabolism, but the pseudogene itself has no independent biological or clinical significance as a drug target[7]. Note: If your intent was to inquire about the active phosphoribosyl pyrophosphate synthetase, the canonical gene is PRPS1 (phosphoribosyl pyrophosphate synthetase 1), which is an actual metabolic enzyme and known disease gene[2][3][6]. The presented Ensembl ID points to a pseudogene, which should not be considered a protein-coding therapeutic target.