Target intelligence / Profile preview

Phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase pseudogene 1 (PAICSP1)

Target
PAICSP1
Molecular classification
Pseudogene (not a functional enzyme), Not classified as enzyme, receptor, transporter, or any functional protein class
01

Overview

Phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazole succinocarboxamide synthetase are enzymes involved in de novo purine biosynthesis. "Pseudogene 1" indicates this genetic locus does not encode a functional protein but is a nonfunctional copy of a gene, likely arising through duplication or retrotransposition. It is not considered a drug target or biomarker because it is not expected to produce a protein, nor participate directly in cellular physiology or disease processes. The name appears to be incorrect or misleading for use as a therapeutic target, drug target, or even a protein annotation. It describes a pseudogene, which, by definition, is not an active gene product. If one intended to reference a functional enzyme, search for the actual gene names PAICS (phosphoribosylaminoimidazole carboxylase/succinocarboxamide synthetase) or related annotated proteins. The abbreviation "PAICSP1" is not standard in the literature. The provided name does not correspond to any canonical drug target, enzyme, receptor, or biomarker in major biological databases; it is a pseudogene, and therefore is neither a therapeutic target nor associated with drugs, mechanisms of action, or clinical biomarkers.

02

Mechanism of action

Not applicable; pseudogenes are not active enzymes or receptors

03

Biological functions

No known biological function, as pseudogenes are typically nonfunctional genetic elements that do not produce active proteins
04

Disease associations

No established disease associationsPseudogenes occasionally have roles in gene regulation, but no data supports a disease role for PAICSP1

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