Phosphorylase kinase regulatory subunit beta pseudogene 1 (PHKBP1)

Phosphorylase kinase regulatory subunit beta pseudogene 1 (PHKBP1) is annotated as a **pseudogene**, which means it is a genomic DNA sequence similar to the functional **phosphorylase kinase beta subunit gene (PHKB)** but does not encode a functional protein[1][8]. Pseudogenes can sometimes regulate their parent genes through non-coding RNA mechanisms, such as serving as microRNA decoys or affecting mRNA stability[2][5]; however, there is no evidence that PHKBP1 itself exerts such effects. It has no direct role in disease as a target, and is not referenced as a drug target, disease biomarker, or molecular receptor/enzyme/transporter. The parent gene, **PHKB**, encodes the beta subunit of phosphorylase b kinase, which plays an important role in glycogen metabolism[7], but PHKBP1, as a pseudogene, does not encode this protein. In summary, PHKBP1 is a non-coding pseudogene with annotation only in genomic databases and is not considered a therapeutic target[1][8].

Other names

phosphorylase kinase, beta pseudogene 1PHKBP1

None (not a pharmacological target; thus, no mechanisms of drug action)