Target intelligence / Profile preview

Phosphorylated microtubule-associated protein tau at threonine 217 (p-tau217)

Target: p-tau217
Molecular classification: Protein, Microtubule-associated protein

Overview

Phosphorylated microtubule-associated protein tau at threonine 217 (p-tau217) is a specific post-translationally modified form of the tau protein, where the amino acid threonine at position 217 is phosphorylated. It serves as a biomarker in neurodegenerative diseases, particularly Alzheimer’s disease, correlating strongly with disease pathology.

Other names: p-tau T217Phospho-tau217

Biological functions

Microtubule stabilizationAxonal transport regulation

Disease associations

Alzheimer's diseaseTauopathiesNeurodegenerative disease

Biomarkers

Alzheimer's disease diagnosisAlzheimer's disease progression monitoring

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